Postpartum haemolytic-uraemic syndrome successfully treated with antithrombin III.

Since first described in 1966 the acute postpartum haemolyticuraemic syndrome (HUS) has been reported in over 40 cases by various authors.' In view of the poor prognosis despite treatment with dialysis, immunosuppression and heparin, streptokinase, dipyridamol, acetylsalicylic acid, or corticosteroids, alone or combined, we report a case in which treatment with a concentrate of antithrombin III (AT-III) appeared to cure the haemolytic anaemia and the thrombocytopenia rapidly, normalise kidney function within a few days, and prevent irreversible kidney damage.